Applications Of Nanomicelles
Researches on the effectivity of nanomicelles in drug delivery have been heavily studied in recent years. Bioengineers have taken great interest on the functionality of nanomicelles due to their small size (10 – 100 nm), capability to solubilize lipophilic drugs in various levels of drug loading, low toxicity, and ability to conjugate with target ligand and stimuli-sensitive regions.
However, because micelles disintegrate rapidly after tissue penetration, using nanomicelles as drug carriers becomes a challenge. Research suggests that in order to efficiently address this, prolonged blood circulation and control for the appropriate release of drugs on target sites should be modulated.